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ADF/Cofilin Binds Phosphoinositides in a Multivalent Manner to Act as a PIP(2)-Density Sensor
Actin-depolymerizing-factor (ADF)/cofilins have emerged as key regulators of cytoskeletal dynamics in cell motility, morphogenesis, endocytosis, and cytokinesis. The activities of ADF/cofilins are regulated by membrane phospholipid PI(4,5)P(2) in vitro and in cells, but the mechanism of the ADF/cofi...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Biophysical Society
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872272/ https://ncbi.nlm.nih.gov/pubmed/20483342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.01.046 |
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