The Effects of ADF/Cofilin and Profilin on the Conformation of the ATP-Binding Cleft of Monomeric Actin

Actin depolymerizing factor (ADF)/cofilin and profilin are small actin-binding proteins, which have central roles in cytoskeletal dynamics in all eukaryotes. When bound to an actin monomer, ADF/cofilins inhibit the nucleotide exchange, whereas most profilins accelerate the nucleotide exchange on act...

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Bibliografiset tiedot
Päätekijät: Kardos, Roland, Pozsonyi, Kinga, Nevalainen, Elisa, Lappalainen, Pekka, Nyitrai, Miklós, Hild, Gábor
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2009
Aiheet:
Protein
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2865994/
https://ncbi.nlm.nih.gov/pubmed/19289059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.12.3906
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