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NORMAL REGIONAL LYMPH NODE ENRICHMENT OF ANTIGEN-SPECIFIC REGULATORY T CELLS WITH AUTOIMMUNE DISEASE-SUPPRESSIVE CAPACITY

Natural CD4+CD25+Foxp3+ regulatory T cells (Treg) effectively prevent autoimmune disease development, but their role in maintaining physiological tolerance against self Ag of internal organs is not yet defined. Herein, we quantified disease-specific Treg (DS-Treg) as Treg that preferentially suppres...

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Autors principals: Wheeler, Karen M., Samy, Eileen T., Tung, Kenneth S. K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872190/
https://ncbi.nlm.nih.gov/pubmed/19923458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0804251
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