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The Bacterial Fermentation Product Butyrate Influences Epithelial Signaling via Reactive Oxygen Species-Mediated Changes in Cullin-1 Neddylation

The human enteric flora plays a significant role in intestinal health and disease. Populations of enteric bacteria can inhibit the NF-κB pathway by blockade of IκB-α ubiquitination, a process catalyzed by the E3-SCF(β)(-TrCP) ubiquitin ligase. The activity of this ubiquitin ligase is regulated via c...

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Detalhes bibliográficos
Main Authors: Kumar, Amrita, Wu, Huixia, Collier-Hyams, Lauren S., Kwon, Young-Man, Hanson, Jason M., Neish, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872164/
https://ncbi.nlm.nih.gov/pubmed/19109186
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