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Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling
The endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG) have opposing effects on cholangiocarcinoma growth. Implicated in cancer, Notch signaling requires the γ-secretase complex for activation. The aims of this study were to determine if the opposing effects of endocannabinoids depen...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872061/ https://ncbi.nlm.nih.gov/pubmed/20347808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.03.017 |
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