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Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling

The endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG) have opposing effects on cholangiocarcinoma growth. Implicated in cancer, Notch signaling requires the γ-secretase complex for activation. The aims of this study were to determine if the opposing effects of endocannabinoids depen...

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Détails bibliographiques
Auteurs principaux: Frampton, Gabriel, Coufal, Monique, Li, Huang, Ramirez, Jonathan, DeMorrow, Sharon
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872061/
https://ncbi.nlm.nih.gov/pubmed/20347808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.03.017
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