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Opposing actions of endocannabinoids on cholangiocarcinoma growth is via the differential activation of Notch signaling

The endocannabinoids anandamide (AEA) and 2-arachidonylglycerol (2-AG) have opposing effects on cholangiocarcinoma growth. Implicated in cancer, Notch signaling requires the γ-secretase complex for activation. The aims of this study were to determine if the opposing effects of endocannabinoids depen...

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Detalhes bibliográficos
Main Authors: Frampton, Gabriel, Coufal, Monique, Li, Huang, Ramirez, Jonathan, DeMorrow, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872061/
https://ncbi.nlm.nih.gov/pubmed/20347808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.03.017
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