Antisense Phosphorodiamidate Morpholino Oligomers Targeted to an Essential Gene Inhibit Burkholderia cepacia complex

BACKGROUND: Members of the Burkholderia cepacia complex (Bcc) cause significant morbidity and mortality in patients with chronic granulomatous disease (CGD) and cystic fibrosis (CF). Many Bcc strains are antibiotic resistant requiring the exploration of novel antimicrobial approaches including antis...

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Hlavní autoři: Greenberg, David E., Marshall-Batty, Kimberly R., Brinster, Lauren R., Zarember, Kol A., Shaw, Pamela A., Mellbye, Brett L., Iversen, Patrick L., Holland, Steven M., Geller, Bruce L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872041/
https://ncbi.nlm.nih.gov/pubmed/20438352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/652807
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