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A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

The level of mRNA encoding the transferrin receptor (TfR) is regulated by iron, and this regulation is mediated by a portion of the 3' untranslated region (UTR) of the TfR transcript. This portion of 3' UTR of the human TfR mRNA contains five RNA elements that have structural similarity to the iron-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Koeller, D M, Casey, J L, Hentze, M W, Gerhardt, E M, Chan, L N, Klausner, R D, Harford, J B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2498873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3574
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