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A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

The level of mRNA encoding the transferrin receptor (TfR) is regulated by iron, and this regulation is mediated by a portion of the 3' untranslated region (UTR) of the TfR transcript. This portion of 3' UTR of the human TfR mRNA contains five RNA elements that have structural similarity to the iron-...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Koeller, D M, Casey, J L, Hentze, M W, Gerhardt, E M, Chan, L N, Klausner, R D, Harford, J B
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287180/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2498873/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3574
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