Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

The translation of ferritin mRNA and degradation of transferrin receptor mRNA are regulated by the interaction of an RNA-binding protein, the iron-responsive element binding protein (IRE-BP), with RNA stem-loop structures known as iron-responsive elements (IREs) contained within these transcripts. I...

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Main Authors: Haile, D J, Rouault, T A, Harford, J B, Kennedy, M C, Blondin, G A, Beinert, H, Klausner, R D
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC50631/
https://ncbi.nlm.nih.gov/pubmed/1281544
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