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Regulation of Kir2.1 channels by the Rho-GTPase, Rac1

Mutations in Kir2.1 inwardly rectifying potassium channels are associated with Andersen Syndrome, a disease characterized by potentially fatal cardiac arrhythmias. While several Andersen-associated mutations affect membrane expression, the cytoplasmic signals that regulate Kir2.1 trafficking are poo...

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Detalhes bibliográficos
Main Authors: Boyer, Stephanie B., Slesinger, Paul A., Jones, S.V. Penelope
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871676/
https://ncbi.nlm.nih.gov/pubmed/18932198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21610
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