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Oxidative Modification of Nuclear Mitogen-activated Protein Kinase Phosphatase 1 Is Involved in Transforming Growth Factor β1-induced Expression of Plasminogen Activator Inhibitor 1 in Fibroblasts

Transforming growth factor β (TGF-β) stimulates reactive oxygen species (ROS) production in various cell types, which mediates many of the effects of TGF-β. The molecular mechanisms whereby TGF-β increases ROS production and ROS modulate the signaling processes of TGF-β, however, remain poorly defin...

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Autors principals: Liu, Rui-Ming, Choi, Jinah, Wu, Jian-He, Gaston Pravia, Kimberly A., Lewis, Karen M., Brand, Jeffrey D., Mochel, N. S. Reyes, Krzywanski, David M., Lambeth, J. David, Hagood, James S., Forman, Henry Jay, Thannickal, Victor J., Postlethwait, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871491/
https://ncbi.nlm.nih.gov/pubmed/20228065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111732
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