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CARMA1 Regulation of Regulatory T Cell Development Involves Modulation of Interleukin-2 Receptor Signaling
T cell receptor-stimulated NF-κB activation requires CARMA1 and is negatively regulated by the deubiquitinase CYLD. Recent studies suggest that CARMA1 regulates regulatory T cell (Treg) development, although the role of NF-κB in this event is incompletely understood. We show that CYLD deficiency cau...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871435/ https://ncbi.nlm.nih.gov/pubmed/20233721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095190 |
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