CARMA1 Regulation of Regulatory T Cell Development Involves Modulation of Interleukin-2 Receptor Signaling

T cell receptor-stimulated NF-κB activation requires CARMA1 and is negatively regulated by the deubiquitinase CYLD. Recent studies suggest that CARMA1 regulates regulatory T cell (Treg) development, although the role of NF-κB in this event is incompletely understood. We show that CYLD deficiency cau...

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Main Authors: Lee, Andrew Joon, Wu, Xuefeng, Cheng, Hanyin, Zhou, Xiaofei, Cheng, Xuhong, Sun, Shao-Cong
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871435/
https://ncbi.nlm.nih.gov/pubmed/20233721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095190
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