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High Resolution Electron Transfer Dissociation Studies of Unfractionated Intact Histones from Murine Embryonic Stem Cells Using On-line Capillary LC Separation: DETERMINATION OF ABUNDANT HISTONE ISOFORMS AND POST-TRANSLATIONAL MODIFICATIONS
Epigenetic regulation of chromatin is dependent on both the histone protein isoforms and state of their post-translational modifications. The assignment of all post-translational modification sites for each individual intact protein isoform remains an experimental challenge. We present an on-line re...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871417/ https://ncbi.nlm.nih.gov/pubmed/20133344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900569-MCP200 |
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