High Resolution Electron Transfer Dissociation Studies of Unfractionated Intact Histones from Murine Embryonic Stem Cells Using On-line Capillary LC Separation: DETERMINATION OF ABUNDANT HISTONE ISOFORMS AND POST-TRANSLATIONAL MODIFICATIONS

Epigenetic regulation of chromatin is dependent on both the histone protein isoforms and state of their post-translational modifications. The assignment of all post-translational modification sites for each individual intact protein isoform remains an experimental challenge. We present an on-line re...

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Détails bibliographiques
Auteurs principaux: Eliuk, Shannon M., Maltby, David, Panning, Barbara, Burlingame, Alma L.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2010
Sujets:
Stem Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871417/
https://ncbi.nlm.nih.gov/pubmed/20133344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900569-MCP200
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