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Erythropoietin pharmacokinetic/pharmacodynamic analysis suggests higher doses in treating neonatal anemia

BACKGROUND: The establishment of effective treatment of neonatal anemia using recombinant human erythropoietin (r-HuEPO) requires a thorough understanding of the physiology and mechanism of EPO’s pharmacologic effect. The purpose of the present preclinical study in sheep was to elucidate the stimula...

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Detalhes bibliográficos
Main Authors: Neelakantan, Srividya, Widness, John A., Schmidt, Robert L., Veng-Pedersen, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871397/
https://ncbi.nlm.nih.gov/pubmed/19371274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1442-200X.2008.02648.x
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