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Receptor-Based Dosing Optimization of Erythropoietin in Juvenile Sheep after Phlebotomy

The primary objective of this work was to determine the optimal time for administration of an erythropoietin (Epo) dose to maximize the erythropoietic effect using a simulation study based on a young sheep pharmacodynamic model. The dosing optimization was accomplished by extending a Hb production p...

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書誌詳細
主要な著者: Rosebraugh, Matthew, Widness, John A., Veng-Pedersen, Peter
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Pharmacology and Experimental Therapeutics 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127239/
https://ncbi.nlm.nih.gov/pubmed/21460232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.110.036855
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