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High-throughput haplotype determination over long distances by Haplotype Fusion PCR and Ligation Haplotyping

When combined with Haplotype Fusion PCR (HF-PCR), Ligation Haplotyping is a robust, high-throughput method for empirical determination of haplotypes, which can be applied to assaying both sequence and structural variation over long distances. Unlike alternative approaches to haplotype determination,...

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Detalhes bibliográficos
Main Authors: Turner, Daniel J., Hurles, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871309/
https://ncbi.nlm.nih.gov/pubmed/20010928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.184
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