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Herpes Simplex Virus-Specific Memory CD8(+) T Cells Are Selectively Activated and Retained in Latently Infected Sensory Ganglia

This study challenges the concept that herpes simplex virus type 1 (HSV-1) latency represents a silent infection that is ignored by the host immune system, and suggests antigen-directed retention of memory CD8(+) T cells. CD8(+) T cells specific for the immunodominant gB(498-505) HSV-1 epitope are s...

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Detalhes bibliográficos
Main Authors: Khanna, Kamal M., Bonneau, Robert H., Kinchington, Paul R., Hendricks, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871305/
https://ncbi.nlm.nih.gov/pubmed/12753737
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