Latent Infection with Herpes Simplex Virus Is Associated with Ongoing CD8(+) T-Cell Stimulation by Parenchymal Cells within Sensory Ganglia

CD8(+) T-cell persistence can be seen in ganglia harboring latent herpes simplex virus (HSV) infection. While there is some evidence that these cells suppress virus reactivation, this view remains controversial. Given that maintenance of latency by CD8(+) T cells would necessitate ongoing exposure t...

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Detalhes bibliográficos
Main Authors: van Lint, Allison L., Kleinert, Lauren, Clarke, Sally R. M., Stock, Angus, Heath, William R., Carbone, Francis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287551/
https://ncbi.nlm.nih.gov/pubmed/16282484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14843-14851.2005
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