Llwytho...

Mechanisms of Enzymatic Degradation of Amyloid Beta Microfibrils Generating Nanofilaments and Nanospheres Related to Cytotoxicity

Amyloid beta (Aβ) fibrils are found in brain tissue of persons with Alzheimer’s disease (AD), where they accumulate as plaques. One way to reduce Aβ accumulation in the brain and potentially treat AD is with Aβ-degrading enzymes such as Neprilysin (NEP) and Insulin-Degrading Enzyme (IDE). However, e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Numata, Keiji, Kaplan, David L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871304/
https://ncbi.nlm.nih.gov/pubmed/20196618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi902134p
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