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Alpha-B-Crystallin Effect on Mature Amyloid Fibrils: Different Degradation Mechanisms and Changes in Cytotoxicity

Given the ability of molecular chaperones and chaperone-like proteins to inhibit the formation of pathological amyloid fibrils, the chaperone-based therapy of amyloidosis has recently been proposed. However, since these diseases are often diagnosed at the stages when a large amount of amyloids is al...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Stepanenko, Olga V., Sulatsky, M. I., Mikhailova, E. V., Stepanenko, Olesya V., Povarova, O. I., Kuznetsova, I. M., Turoverov, K. K., Sulatskaya, A. I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589196/
https://ncbi.nlm.nih.gov/pubmed/33081200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207659
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