Preclinical Evaluation of an (131)I-Labeled Benzamide for Targeted Radiotherapy of Metastatic Melanoma

Radiolabeled benzamides are attractive candidates for targeted radiotherapy of metastatic melanoma as they bind melanin and exhibit high tumor uptake and retention. One such benzamide, N-(2-diethylamino-ethyl)-4-(4-fluoro-benzamido)-5-iodo-2-methoxy-benzamide (MIP-1145), was evaluated for its abilit...

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Dades bibliogràfiques
Autors principals: Joyal, John L., Barrett, John A., Marquis, John C., Chen, Jianqing, Hillier, Shawn M., Maresca, Kevin P., Boyd, Marie, Gage, Kenneth, Nimmagadda, Sridhar, Kronauge, James F., Friebe, Matthias, Dinkelborg, Ludger, Stubbs, James B., Stabin, Michael G., Mairs, Rob, Pomper, Martin G., Babich, John W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871064/
https://ncbi.nlm.nih.gov/pubmed/20442292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4414
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