Preclinical Evaluation of Novel Glutamate-Urea-Lysine Analogs that Target Prostate Specific Membrane Antigen as Molecular Imaging Pharmaceuticals for Prostate Cancer

Prostate-specific membrane antigen (PSMA) is expressed in normal human prostate epithelium and is highly upregulated in prostate cancer. We previously reported a series of novel small molecule inhibitors targeting PSMA. Two compounds, MIP-1072, (S)-2-(3-((S)-1-carboxy-5-(4–iodobenzylamino)pentyl)ure...

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Detalhes bibliográficos
Main Authors: Hillier, Shawn M., Maresca, Kevin P., Femia, Frank J., Marquis, John C., Foss, Catherine A., Nguyen, Nghi, Zimmerman, Craig N., Barrett, John A., Eckelman, William C., Pomper, Martin G., Joyal, John L., Babich, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114247/
https://ncbi.nlm.nih.gov/pubmed/19706750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1682
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