Preclinical Evaluation of an (131)I-Labeled Benzamide for Targeted Radiotherapy of Metastatic Melanoma

Radiolabeled benzamides are attractive candidates for targeted radiotherapy of metastatic melanoma as they bind melanin and exhibit high tumor uptake and retention. One such benzamide, N-(2-diethylamino-ethyl)-4-(4-fluoro-benzamido)-5-iodo-2-methoxy-benzamide (MIP-1145), was evaluated for its abilit...

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Detalhes bibliográficos
Main Authors: Joyal, John L., Barrett, John A., Marquis, John C., Chen, Jianqing, Hillier, Shawn M., Maresca, Kevin P., Boyd, Marie, Gage, Kenneth, Nimmagadda, Sridhar, Kronauge, James F., Friebe, Matthias, Dinkelborg, Ludger, Stubbs, James B., Stabin, Michael G., Mairs, Rob, Pomper, Martin G., Babich, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871064/
https://ncbi.nlm.nih.gov/pubmed/20442292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4414
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