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Regulation of the function of eukaryotic DNA topoisomerase I: topological conditions for inactivity.

The effects of supercoiling on the cleavage reaction by eukaryotic DNA topoisomerases I (wheat germ, chicken erythrocyte, and calf thymus) have been analyzed on DNA fragments (0.96 and 2.3 kilobases) encompassing an immunoglobulin kappa light-chain promoter. In one topological condition of the subst...

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Main Authors: Camilloni, G, Di Martino, E, Di Mauro, E, Caserta, M
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC287068/
https://ncbi.nlm.nih.gov/pubmed/2541429
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