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Synthesis and binding studies of two new macrocyclic receptors for the stereoselective recognition of dipeptides

We present here the design, synthesis, and analysis of a series of receptors for peptide ligands inspired by the hydrogen-bonding pattern of protein β-sheets. The receptors themselves can be regarded as strands 1 and 3 of a three-stranded β-sheet, with cross-linking between the chains through the 4-...

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Detalhes bibliográficos
Main Authors: Castilla, Ana Maria, Morgan Conn, M, Ballester, Pablo
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2870531/
https://ncbi.nlm.nih.gov/pubmed/20485587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.6.5
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