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Pertussis toxin induces structural changes in G alpha proteins independently of ADP-ribosylation.

Pertussis toxin catalyzes ADP-ribosylation of a family of GTP-binding proteins (G alpha proteins) involved in signal transduction. It is thought that this activity is responsible for the attenuating effects of the toxin on the actions of a number of hormones and neurotransmitters. By utilizing speci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ribeiro-Neto, F A, Rodbell, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2523074/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2577
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