Mechanisms of Pertussis Toxin Action: ADP-Ribosylation and Its Role in Pertussis Pathogenesis
Pertussis toxin (PTx) is a major virulence factor of <i>Bordetella pertussis</i> and an AB5-type exotoxin that disrupts host signaling. Its enzymatic A subunit ADP-ribosylates the α-subunit of inhibitory G proteins (Gα<sub>i</sub>), preventing them from mediating receptor-induced inhibition of adeny...
Gardado en:
| Principais autores: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI AG
2026-03-01
|
| Series: | Toxins |
| Assuntos: | |
| Acceso en liña: | https://www.mdpi.com/2072-6651/18/3/148 |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|