13q14 deletions in CLL involve cooperating tumor suppressors

B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia. 13q14 deletions are most common chromosomal alterations in CLL. We previously reported that miR-15/16 is a target of 13q14 deletions and plays a tumor suppressor role by targeting BCL2. Because DLEU7 is located near miR-15/...

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Autors principals: Palamarchuk, Alexey, Efanov, Alexey, Nazaryan, Natalya, Santanam, Urmila, Alder, Hansjuerg, Rassenti, Laura, Kipps, Thomas, Croce, Carlo M., Pekarsky, Yuri
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869560/
https://ncbi.nlm.nih.gov/pubmed/20071661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-249367
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