Effective Melanoma Immunotherapy in Mice by the Skin-Depigmenting Agent Monobenzone and the Adjuvants Imiquimod and CpG

BACKGROUND: Presently melanoma still lacks adequate treatment options for metastatic disease. While melanoma is exceptionally challenging to standard regimens, it is suited for treatment with immunotherapy based on its immunogenicity. Since treatment-related skin depigmentation is considered a favou...

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Hlavní autoři: van den Boorn, Jasper G., Konijnenberg, Debby, Tjin, Esther P. M., Picavet, Daisy I., Meeuwenoord, Nico J., Filippov, Dmitri V., van der Veen, J. P. Wietze, Bos, Jan D., Melief, Cornelis J. M., Luiten, Rosalie M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869359/
https://ncbi.nlm.nih.gov/pubmed/20498710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010626
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