Age- and Temperature-Dependent Somatic Mutation Accumulation in Drosophila melanogaster

Using a transgenic mouse model harboring a mutation reporter gene that can be efficiently recovered from genomic DNA, we previously demonstrated that mutations accumulate in aging mice in a tissue-specific manner. Applying a recently developed, similar reporter-based assay in Drosophila melanogaster...

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Bibliografske podrobnosti
Main Authors: Garcia, Ana Maria, Calder, R. Brent, Dollé, Martijn E. T., Lundell, Martha, Kapahi, Pankaj, Vijg, Jan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869313/
https://ncbi.nlm.nih.gov/pubmed/20485564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000950
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