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Age- and Temperature-Dependent Somatic Mutation Accumulation in Drosophila melanogaster
Using a transgenic mouse model harboring a mutation reporter gene that can be efficiently recovered from genomic DNA, we previously demonstrated that mutations accumulate in aging mice in a tissue-specific manner. Applying a recently developed, similar reporter-based assay in Drosophila melanogaster...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869313/ https://ncbi.nlm.nih.gov/pubmed/20485564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000950 |
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