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Interpretation of Association Signals and Identification of Causal Variants from Genome-wide Association Studies
GWAS have been successful in identifying disease susceptibility loci, but it remains a challenge to pinpoint the causal variants in subsequent fine-mapping studies. A conventional fine-mapping effort starts by sequencing dozens of randomly selected samples at susceptibility loci to discover candidat...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2869011/ https://ncbi.nlm.nih.gov/pubmed/20434130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.04.003 |
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