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The ras and myc oncogenes cooperate in tumor induction in many tissues when introduced into midgestation mouse embryos by retroviral vectors.

Midgestation embryos were infected with replication-defective retroviral vectors that either transduced the myc oncogene, the ras oncogene, or both oncogenes simultaneously. The myc virus induced tumors in diverse organs at a very low frequency and with a long latency period, while approximately 20%...

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Bibliografische gegevens
Hoofdauteurs: Compere, S J, Baldacci, P, Sharpe, A H, Thompson, T, Land, H, Jaenisch, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC286884/
https://ncbi.nlm.nih.gov/pubmed/2648394
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