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Tumor morphological evolution: directed migration and gain and loss of the self-metastatic phenotype

BACKGROUND: Aside from the stepwise genetic alterations known to underlie cancer cell creation, the microenvironment is known to profoundly influence subsequent tumor development, morphology and metastasis. Invasive cluster formation has been assumed to be dependent on directed migration and a heter...

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Detalhes bibliográficos
Main Authors: Enderling, Heiko, Hlatky, Lynn, Hahnfeldt, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868833/
https://ncbi.nlm.nih.gov/pubmed/20406441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-5-23
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