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Evolution and Phenotypic Selection of Cancer Stem Cells

Cells of different organs at different ages have an intrinsic set of kinetics that dictates their behavior. Transformation into cancer cells will inherit these kinetics that determine initial cell and tumor population progression dynamics. Subject to genetic mutation and epigenetic alterations, canc...

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Publicat a:PLoS Comput Biol
Autors principals: Poleszczuk, Jan, Hahnfeldt, Philip, Enderling, Heiko
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351192/
https://ncbi.nlm.nih.gov/pubmed/25742563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004025
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