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Evolution and Phenotypic Selection of Cancer Stem Cells

Cells of different organs at different ages have an intrinsic set of kinetics that dictates their behavior. Transformation into cancer cells will inherit these kinetics that determine initial cell and tumor population progression dynamics. Subject to genetic mutation and epigenetic alterations, canc...

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Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Poleszczuk, Jan, Hahnfeldt, Philip, Enderling, Heiko
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351192/
https://ncbi.nlm.nih.gov/pubmed/25742563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004025
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