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Systems Biology of Tumor Dormancy: linking biology and mathematics on multiple scales to improve cancer therapy

For many decades it has been appreciated that tumor progression is not monotonic, and development of a cancer cell does not equate to inevitable cancer presentation in the clinic (1). Tumor progression is challenged by numerous intrinsic and extrinsic bottlenecks that can hold the tumor in dormant s...

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Detalhes bibliográficos
Main Authors: Enderling, Heiko, Hahnfeldt, Philip, Hlatky, Lynn, Almog, Nava
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374524/
https://ncbi.nlm.nih.gov/pubmed/22414579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3269
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