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Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance

BACKGROUND: Subsets of cells with stem-like properties have been previously isolated from human epithelial cancers and their resistance to apoptosis-inducing stimuli has been related to carcinoma recurrence and treatment failure. The aim of this study was to investigate the mechanisms of resistance...

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Detalhes bibliográficos
Main Authors: Harper, Lisa J, Costea, Daniela Elena, Gammon, Luke, Fazil, Bilal, Biddle, Adrian, Mackenzie, Ian C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868812/
https://ncbi.nlm.nih.gov/pubmed/20426848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-166
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