Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma

Cancer stem cells (CSCs) drive tumour spread and therapeutic resistance, and can undergo epithelial-to-mesenchymal transition (EMT) and mesenchymal-to-epithelial transition (MET) to switch between epithelial and post-EMT sub-populations. Examining oral squamous cell carcinoma (OSCC), we now show tha...

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Publicat a:EBioMedicine
Autors principals: Biddle, Adrian, Gammon, Luke, Liang, Xiao, Costea, Daniela Elena, Mackenzie, Ian C.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776071/
https://ncbi.nlm.nih.gov/pubmed/26981578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.01.007
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