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Activity of the acyl-CoA synthetase ACSL6 isoforms: role of the fatty acid Gate-domains

BACKGROUND: Activation of fatty acids by acyl-CoA synthetase enzymes is required for de novo lipid synthesis, fatty acid catabolism, and remodeling of biological membranes. Human long-chain acyl-CoA synthetase member 6, ASCL6, is a form present in the plasma membrane of cells. Splicing events affect...

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Detalhes bibliográficos
Main Authors: Soupene, Eric, Dinh, Nghi Phuong, Siliakus, Melvin, Kuypers, Frans A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868784/
https://ncbi.nlm.nih.gov/pubmed/20429931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-18
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