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Mammalian Long-Chain Acyl-CoA Synthetases

Acyl-CoA synthetase enzymes are essential for de novo lipid synthesis, fatty acid catabolism, and remodeling of membranes. Activation of fatty acids requires a two-step reaction catalyzed by these enzymes. In the first step, an acyl-AMP intermediate is formed from ATP. AMP is then exchanged with CoA...

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Detalhes bibliográficos
Main Authors: Soupene, Eric, Kuypers, Frans A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377585/
https://ncbi.nlm.nih.gov/pubmed/18375835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0710-MR-287
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