IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation

Bax, a pro-apoptotic protein from the Bcl-2 family, is central to apoptosis regulation. To suppress spontaneous apoptosis, Bax must be under stringent control that may include regulation of Bax conformation and expression levels. We report that IBRDC2, an IBR-type RING-finger E3 ubiquitin ligase, re...

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Bibliografiska uppgifter
Huvudupphovsmän: Benard, Giovanni, Neutzner, Albert, Peng, Guihong, Wang, Chunxin, Livak, Ferenc, Youle, Richard J, Karbowski, Mariusz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868578/
https://ncbi.nlm.nih.gov/pubmed/20300062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.39
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