Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella

3-phosphorylated phosphoinositides (3-PtdIns) orchestrate endocytic trafficking pathways exploited by intracellular pathogens such as Salmonella to gain entry into the cell. To infect the host, Salmonellae subvert its normal macropinocytic activity, manipulating the process to generate an intracellu...

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Autori principali: Kerr, Markus C, Wang, Jack T H, Castro, Natalie A, Hamilton, Nicholas A, Town, Liam, Brown, Darren L, Meunier, Frederic A, Brown, Nat F, Stow, Jennifer L, Teasdale, Rohan D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868569/
https://ncbi.nlm.nih.gov/pubmed/20300065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.28
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