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Disruption of Mouse Corneal Epithelial Differentiation by Conditional Inactivation of Pnn

PURPOSE. To investigate the specific role of Pinin (Pnn) in the development of anterior eye segment in mice. METHODS. Conditional inactivation of Pnn in the developing surface eye ectoderm and lens was achieved by creating mice carrying a Pnn null and a floxed Pnn allele as well as a Pax6-Cre-GFP (L...

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Библиографические подробности
Главные авторы: Joo, Jeong-Hoon, Kim, Yong H., Dunn, Nicholas W., Sugrue, Stephen P.
Формат: Artigo
Язык:Inglês
Опубликовано: Association for Research in Vision and Ophthalmology, Inc. 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868409/
https://ncbi.nlm.nih.gov/pubmed/19892877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4591
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