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Disruption of Mouse Corneal Epithelial Differentiation by Conditional Inactivation of Pnn

PURPOSE. To investigate the specific role of Pinin (Pnn) in the development of anterior eye segment in mice. METHODS. Conditional inactivation of Pnn in the developing surface eye ectoderm and lens was achieved by creating mice carrying a Pnn null and a floxed Pnn allele as well as a Pax6-Cre-GFP (L...

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Autores principales: Joo, Jeong-Hoon, Kim, Yong H., Dunn, Nicholas W., Sugrue, Stephen P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Association for Research in Vision and Ophthalmology, Inc. 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868409/
https://ncbi.nlm.nih.gov/pubmed/19892877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4591
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