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Transcriptomic Analysis of PNN- and ESRP1-Regulated Alternative Pre-mRNA Splicing in Human Corneal Epithelial Cells

PURPOSE. We investigated the impact of PININ (PNN) and epithelial splicing regulatory protein 1 (ESRP1) on alternative pre-mRNA splicing in the corneal epithelial context. METHODS. Isoform-specific RT-PCR assays were performed on wild-type and Pnn knockout mouse cornea. Protein interactions were exa...

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Detalhes bibliográficos
Main Authors: Joo, Jeong-Hoon, Correia, Greg P., Li, Jian-Liang, Lopez, Maria-Cecilia, Baker, Henry V., Sugrue, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559072/
https://ncbi.nlm.nih.gov/pubmed/23299472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10695
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