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Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1

Human small C-terminal domain phosphatase 1 (Scp1) modulates the phosphorylation state of the C-terminal domain (CTD) of eukaryotic RNA polymerase II (RNAP II), with preference for phosphorylated Ser5 in the tandem heptad repeats of the CTD. Additionally, Scp1 was identified as a conserved regulator...

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Hlavní autoři: Zhang, Mengmeng, Liu, June, Kim, Youngjun, Dixon, Jack E, Pfaff, Samuel L, Gill, Gordon N, Noel, Joseph P, Zhang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868240/
https://ncbi.nlm.nih.gov/pubmed/20222012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.375
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