Determinants for Dephosphorylation of the RNA Polymerase II C-Terminal Domain by Scp1

Phosphorylation and dephosphorylation of the C-terminal domain (CTD) of RNA polymerase II (Pol II) represent a critical regulatory checkpoint for transcription. Transcription initiation requires Fcp1/Scp1-mediated dephosphorylation of phospho-CTD. Fcp1 and Scp1 belong to a family of Mg(2+)-dependent...

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Main Authors: Zhang, Yan, Kim, Youngjun, Genoud, Nicolas, Gao, Jianmin, Kelly, Jeffery W., Pfaff, Samuel L., Gill, Gordon N., Dixon, Jack E., Noel, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859291/
https://ncbi.nlm.nih.gov/pubmed/17157258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.10.027
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